What’s coronary disease? What can cause coronary disease?


MNT Knowledge CenterCardiovascular diseases include illnesses that involve the blood vessels (veins, arteries and capillaries) or the heart, or both – diseases that affect the cardiovascular system.

The cardiovascular system, also called the circulatory system,may be the system that moves bloodstream throughout the body. It consists of the center, arterial blood vessels, veins, and capillaries. It transports oxygenated bloodstream in the lung area and heart through the entire body with the arterial blood vessels. Bloodstream experiences the capillaries – ships situated between your veins and arterial blood vessels.

Once the bloodstream continues to be depleted of oxygen, it can make its long ago towards the heart and lung area with the veins.

The circulatory system might also range from the circulation of lymph, that is basically recycled bloodstream plasma once it has been strained in the bloodstream cells and came back towards the the lymphatic system. The heart doesn’t range from the the lymphatic system. In the following paragraphs, the circulatory system doesn’t range from the circulation of lymph.

Examples of diseases that affect the cardiovascular system

    • Cardiac diseases (Heart diseases) – examples include:

      – Angina (considered as both a cardiac and vascular disease)
      – Arrhythmia (problems with the heartbeat, irregular heartbeat)
      – Congenital heart disease
      – Coronary artery disease (CAD)
      – Dilated cardiomyopathy
      – Heart attack (myocardial infarction)
      – Heart failure
      – Hypertrophic cardiomyopathy
      – Mitral regurgitation
      – Mitral valve prolapse
      – Pulmonary stenosis


  • Vascular diseases (diseases that affect the blood vessels – arteries, veins or capillaries), examples include:

    – Peripheral artery (arterial) disease
    – Aneurism
    – Atherosclerosis
    – Renal artery disease
    – Raynaud’s disease (Raynaud’s phenomenon)
    – Buerger’s disease
    – Peripheral venous disease
    – Stroke – known as a type of cerebrovascular disease
    – Venous blood clots
    – Bloodclotting disorders.


What are the risk factor for cardiovascular disease?

A danger factor is one thing that increases your odds of creating a disease, disorder or condition. Weight problems is really a risk factor for diabetes type 2

Scientists in the Northwestern College Feinberg Med school reported in JAMA the lifetime risk for coronary disease is much more than 50% for both women and men. They added that even among individuals with couple of or no cardiovascular risks, the danger continues to be greater than 30%.

Based on the Nhs (NHS), United kingdom, you will find nine primary risks connected with coronary disease, they’re:

    • Hypertension (high blood pressure) – this is the one major risk factor for CVD by far. If hypertension is poorly controlled, the artery walls may become damaged, raising the risk of developing a blood clot


  • Radiation therapy – scientists from the Karolinska Institutet, Sweden, reported in the Journal of the American College of Cardiology that radiation therapy can increase the risk of cardiovascular disease later in life.



  • Smoking – regular smoking can narrow the blood vessels, especially the coronary arteries.



  • Lack of sleep – people who sleep less than 7.5 hours each day have a higher risk of developing cardiovascular disease, researchers from Jichi Medical University, Tochigi, Japan, reported in Archives of Internal Medicine.



  • Hyperlipidemia (high blood cholesterol) – there is a higher chance of narrowing of the blood vessels and blood clots



  • Having a partner with cancer – a person whose partner has cancer has a nearly 30% higher risk of developing stroke or coronary heart disease, investigators from the Centre for Primary Healthcare Research in Malmö, Sweden, revealed in the journal Circulation.



  • Diabetes – this includes both types 1 and 2. High blood sugar levels can harm the arteries. People with type 2 diabetes are often overweight or obese, which are also risk factors for cardiovascular disease. People with diabetes are 2 to 4 times more likely to die from heart disease than non-diabetics.


Experts say that blood glucose control measurements can help predict a diabetes patient’s cardiovascular disease risk.


  • Unhealthy eating – diets which are high in fat combined with carbohydrates, especially if they consist mainly of fast foods, can accelerate the accumulation of fatty deposits inside the arteries, which raise the risk of obesity, hypertension and hyperlipidemia. Diets which lack adequate amounts of fruit, vegetables, fiber, whole grains and essential nutrients are not good for cardiovascular health.


Research printed in BMC Medicine (March 2013 issue) discovered that consuming processed meat is connected with developing coronary disease and cancer.

Is reduced salt intake from the fall in deaths from coronary disease? – Between 2003 and 2011, average salt intake fell by 15% in England, and deaths from cardiovascular disease and stroke fell by around 40%. An investigation team from Queen Mary College based in london investigated the bond as well as their research was printed in BMJ in April 2014.

High sodium intake ’causes 10 % global cardiovascular deaths each year’ – The Planet Health Organization suggest that grown ups should consume under 2 g of sodium each day. But new research finds that sodium intake above this recommendation makes up about almost 10 % cardiovascular deaths globally every year.


  • Physical inactivity – people who lead predominantly sedentary lives tend to have higher blood pressure, more stress hormones, higher blood cholesterol levels, and are more likely to be overweight. These are all risk factors for cardiovascular diseases.



  • Drinking too much alcohol – people who drink too much tend to have higher blood pressure and blood cholesterol levels.



  • Stress – hormones associated with (mental) stress, such as cortisone, raise blood sugar levels. Stress is also linked to higher blood pressure.



  • Air pollution – Belgian researchers reported in The Lancet that air pollution causes about the same number of heart attacks as other individual risk factors. The investigators assessed 36 separate studies that focused on air pollution.



  • COPD and reduced lung function – a study presented at the European Respiratory Society’s Annual Congress in Amsterdam, showed that people with COPD (chronic obstructive pulmonary disease) have a significant risk of developing cardiovascular disease. The researchers, from the Sunderby Hospital in Sweden, added that patients with reduced lung function are also at higher risk.



  • The age of first menstruation – females who start menstruating early are more likely to become obese, and have cardiovascular disease risk factors, researchers reported in the Journal of Clinical Endocrinology & Metabolism.


People with one cardiovascular risk factor, typically have one or two others too. For example, very obese people often have high blood pressure, high blood cholesterol, and diabetes type 2.

Experts agree that the most common risk factors for cardiovascular disease are atherosclerosis and/or hypertension.

Recent developments on cardiovascular disease causes from MNT news

Youthful depressed women ‘more prone to suffer heart attack’

New research looking into links between depression and cardiovascular disease finds that ladies aged 55 and more youthful tend to be more than two times as likely to be affected by major cardiac problems should they have moderate or severe depression.

These cardiac problems include dying from cardiovascular disease, cardiac arrest and needing an artery-opening procedure.

Smoking and preterm birth combine to triple chance of maternal CVD

A mix of smoking and providing birth preterm can greater than triple the chance of coronary disease faced by moms, based on the findings of new research printed within the European Journal of Preventive Cardiology.

Low oxygen before birth, high-salt diet may pose risk for coronary disease

Poor diet includes a obvious effect on human health, and just what nourishes people as children, as well as the womb, can impact them in later existence. New information indicates that insufficient oxygen within the womb, coupled with high salt intake in later existence, can result in vascular problems.

What is the health burden of cardiovascular disease worldwide?

According to WHO (World Health Organization):

    • Cardiovascular diseases (CVDs) are the leading cause of deaths globally – more people die from CVDs than anything else


  • In 2008, approximately 17.3 million people died from CVDs worldwide; just under one third (30%) of all registered premature deaths. Of these deaths:


– 7.3 million died from coronary heart disease

– 6.2 million from stroke


  • The majority (80%) of CVD deaths occur in low and middle-income countries



  • CVDs occur equally in men and women



  • Twenty-five million people will die from CVDs annually by 2030 – most of the deaths being due to stroke and heart disease.



  • The majority of CVDs are preventable if people addressed their risk factors



  • Hypertension (raised blood pressure) is responsible for 7.5 million deaths each year



420,000 women die from cardiovascular disease in the USA annually. Nearly 50% of American women die from heart disease or stroke, compared to 4% from breast cancer.

Cardiovascular disease prevention in adults

Lowering your chance of developing coronary disease involves addressing the danger factors in the above list, i.e. eating a healthy diet plan, doing lots of exercise, achieving a sound body weight after which keeping it up, and never smoking.

For those who have coronary disease, cacao flavanols can be a vital a part of a healthy diet plan, scientists in the College of California Bay Area reported within the Journal from the American College of Cardiology (JACC).

Should you consume alcohol, don’t exceed the suggested daily limits of two to three models each day for ladies and three or four for males.

Eating fruit every single day ‘could reduce chance of CVD by as much as 40%’. The study team, brought by Dr. Huaidong Du in the College of Oxford within the United kingdom, presented the findings of the attend the ecu Society of Cardiology Congress 2014.

Cardiovascular disease prevention in children

Studies have proven that lesions can be displayed within the aortas and right coronary arterial blood vessels of kids as youthful as 7 to nine years old.

Improper habits during childhood won’t result in coronary disease as the individual is a young child, however a trend takes hold that establishes the buildup of issues that continue into their adult years, producing a much greater possibility of getting a coronary disease later in existence.

Children who consume a lot of salt have a greater chance of hypertension when they’re grown ups, in addition to cardiovascular disease and stroke. Parents also needs to keep an eye on just how much saturated fats and sugar a young child consumes.

A young child, if because of the right atmosphere, is of course physically active. Within our society, kids spend a lot of time watching television, playing game titles, and being chauffeured around by their parents. Something their grandparent rarely or never did once they were small.

United kingdom health government bodies state that children aged five or fewer who is able to walk unaided ought to be physically active not less than three hrs every day – these hrs ought to be disseminate.

Children aged from 5 to 18 years must do a minumum of one hour of aerobic activity daily – their activities will include a variety of intensities, from the same as fast-travelling to running.

Swedish researchers reported that healthy children can begin to exhibit a larger chance of future heart disease if they’re physically inactive.

Recent developments on cardiovascular disease prevention from MNT news

Testosterone therapy may reduce cardiovascular risk in older men

Scientists have discovered that men whose lower levels of testosterone were given testosterone substitute therapy also possessed a reduced chance of cardiac arrest, stroke and all sorts of-cause mortality.

Keep working out, say heart experts

A brand new clinical perspective in the Journal from the American College of Cardiology verifies that many individuals developed nations ought to be more worried about the possible lack of exercise within their lives compared to the possibility harm exercise may cause.

Eating fruits daily may lower your chance of cardiovascular dying

New information provides further proof of the health advantages of fruit consumption, after discovering that eating fruits daily may lower the potential risks of cardiac arrest, stroke and cardiovascular dying.

Does aspirin protect from cardiovascular disease?

Aspirin, also known as acetylsalicylic acid (ASA) is a medication that is generally used as an analgesic (painkiller that does not produce anesthesia or loss of consciousness) for minor pains; it is also used as an antipyretic (to reduce fever) and as an anti-inflammatory.

Aspirin has also become more and more popular as an antiplatelet – to prevent blood-clot formation. High-risk patients take it in low doses to prevent strokes and heart attacks.

Aspirin is also given to patients after a heart attack to prevent cardiac tissue death or heart attack recurrence.

A major problem posed by aspirin therapy for patients at risk of heart attack, stroke and other cardiovascular events is major bleeding. A considerable proportion of patients with diabetes have a high rate of major bleeding, regardless of their therapeutic aspirin status.

There have been literally hundreds of studies on the benefits, harms and inefficacy of aspirin over the last twenty years. While some have shown benefits for the cardiovascular system, especially among patients with existing conditions, others have concluded that healthy people should not take regular low-dose aspirin.

Below are links to some studies on the benefits and harms of aspirin for reducing the risk of cardiovascular diseases and events:

  • “An aspirin a day will keep heart attack away”
  • “Use of low dose aspirin to protect against cardiovascular disease should be abandoned”
  • “For healthy people daily aspirin may do more harm than good”
  • “For patients with type 2 diabetes in Japan, taking low-dose aspirin does not significantly reduce cardiovascular risk”
  • “Aspirin only benefits diabetics with history of heart disease or stroke”
  • “Women taking daily aspirin have lower death risks says new study”
  • “For most heart failure patients, aspirin and warfarin equally effective”

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